A Definitive Haplotype Map as Determined by Genotyping Duplicated Haploid Genomes Finds a Predominant Haplotype Preference at Copy-Number Variation Events

The majority of complete hydatidiform moles (CHMs) harbor duplicated haploid genomes that originate from sperm. This makes CHMs more advantageous than conventional diploid cells for determining haplotypes of SNPs and copy-number variations (CNVs), because all of the genetic variants in a CHM genome...

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Detalhes bibliográficos
Main Authors: Kukita, Yoji, Yahara, Koji, Tahira, Tomoko, Higasa, Koichiro, Sonoda, Miki, Yamamoto, Ken, Kato, Kiyoko, Wake, Norio, Hayashi, Kenshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032077/
https://ncbi.nlm.nih.gov/pubmed/20537301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.05.003
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