A Definitive Haplotype Map as Determined by Genotyping Duplicated Haploid Genomes Finds a Predominant Haplotype Preference at Copy-Number Variation Events

The majority of complete hydatidiform moles (CHMs) harbor duplicated haploid genomes that originate from sperm. This makes CHMs more advantageous than conventional diploid cells for determining haplotypes of SNPs and copy-number variations (CNVs), because all of the genetic variants in a CHM genome...

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Библиографические подробности
Главные авторы: Kukita, Yoji, Yahara, Koji, Tahira, Tomoko, Higasa, Koichiro, Sonoda, Miki, Yamamoto, Ken, Kato, Kiyoko, Wake, Norio, Hayashi, Kenshi
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032077/
https://ncbi.nlm.nih.gov/pubmed/20537301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.05.003
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