Glutamine enhances selectivity of chemotherapy through changes in glutathione metabolism.

OBJECTIVE: Chemotherapy doses are limited by toxicity to normal tissues. Intravenous glutamine protects liver cells from oxidant injury by increasing intracellular glutathione (GSH) content. The authors hypothesized that supplemental oral glutamine (GLN) would increase the therapeutic index of metho...

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Bibliographic Details
Main Authors: Rouse, K, Nwokedi, E, Woodliff, J E, Epstein, J, Klimberg, V S
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234593/
https://ncbi.nlm.nih.gov/pubmed/7726679
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