Glutamine enhances selectivity of chemotherapy through changes in glutathione metabolism.

OBJECTIVE: Chemotherapy doses are limited by toxicity to normal tissues. Intravenous glutamine protects liver cells from oxidant injury by increasing intracellular glutathione (GSH) content. The authors hypothesized that supplemental oral glutamine (GLN) would increase the therapeutic index of metho...

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Bibliografiske detaljer
Main Authors: Rouse, K, Nwokedi, E, Woodliff, J E, Epstein, J, Klimberg, V S
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234593/
https://ncbi.nlm.nih.gov/pubmed/7726679
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