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Use dependence of tetrodotoxin block of sodium channels: a revival of the trapped-ion mechanism.
The use-dependent block of sodium channels by tetrodotoxin (TTX) has been studied in cRNA-injected Xenopus oocytes expressing the alpha-subunit of rat brain IIA channels. The kinetics of stimulus-induced extra block are consistent with an underlying relaxation process involving only three states. Cu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1233597/ https://ncbi.nlm.nih.gov/pubmed/8874004 |
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