Deletion of the M(5) muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia

Little is known about the physiological roles of the M(5) muscarinic receptor, the last member of the muscarinic receptor family (M(1)–M(5)) to be cloned. In the brain, the M(5) receptor subtype is preferentially expressed by dopaminergic neurons of the substantia nigra and the ventral tegmental are...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Basile, Anthony S., Fedorova, Irina, Zapata, Agustin, Liu, Xiaoguang, Shippenberg, Toni, Duttaroy, Alokesh, Yamada, Masahisa, Wess, Jürgen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123277/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12154229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162371899
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