Deletion of the M(5) muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia

Little is known about the physiological roles of the M(5) muscarinic receptor, the last member of the muscarinic receptor family (M(1)–M(5)) to be cloned. In the brain, the M(5) receptor subtype is preferentially expressed by dopaminergic neurons of the substantia nigra and the ventral tegmental are...

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Опубліковано в::	Proc Natl Acad Sci U S A
Автори:	Basile, Anthony S., Fedorova, Irina, Zapata, Agustin, Liu, Xiaoguang, Shippenberg, Toni, Duttaroy, Alokesh, Yamada, Masahisa, Wess, Jürgen
Формат:	Artigo
Мова:	Inglês
Опубліковано:	National Academy of Sciences 2002
Предмети:	Biological Sciences
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123277/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12154229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162371899
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