Deletion of the M(5) muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia

Little is known about the physiological roles of the M(5) muscarinic receptor, the last member of the muscarinic receptor family (M(1)–M(5)) to be cloned. In the brain, the M(5) receptor subtype is preferentially expressed by dopaminergic neurons of the substantia nigra and the ventral tegmental are...

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Basile, Anthony S., Fedorova, Irina, Zapata, Agustin, Liu, Xiaoguang, Shippenberg, Toni, Duttaroy, Alokesh, Yamada, Masahisa, Wess, Jürgen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123277/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12154229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162371899
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