Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes

Recent investigation has focused on identifying signaling pathways that inhibit cardiac hypertrophy, a major risk factor for cardiovascular morbidity and mortality. In this context, nitric oxide (NO), signaling via cGMP and cGMP-dependent protein kinase type I (PKG I), has been recognized as a negat...

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Библиографические подробности
Главные авторы: Fiedler, Beate, Lohmann, Suzanne M., Smolenski, Albert, Linnemüller, Stephan, Pieske, Burkert, Schröder, Frank, Molkentin, Jeffery D., Drexler, Helmut, Wollert, Kai C.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2002
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC123262/
https://ncbi.nlm.nih.gov/pubmed/12177418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162100799
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