Wiskott–Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses

The Wiskott–Aldrich syndrome (WAS) is a primary immunodeficiency disorder caused by a mutation in WAS protein (WASp) that results in defective actin polymerization. Although the function of many hematopoietic cells requires WASp, the specific expression and function of this molecule in natural kille...

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Opis bibliograficzny
Wydane w:	Proc Natl Acad Sci U S A
Główni autorzy:	Orange, Jordan S., Ramesh, Narayanaswamy, Remold-O'Donnell, Eileen, Sasahara, Yoji, Koopman, Louise, Byrne, Michael, Bonilla, Francisco A., Rosen, Fred S., Geha, Raif S., Strominger, Jack L.
Format:	Artigo
Język:	Inglês
Wydane:	National Academy of Sciences 2002
Hasła przedmiotowe:	Biological Sciences
Dostęp online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123260/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12177428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162376099
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Wiskott–Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses

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