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Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient mice
The helix–loop–helix proteins E47 and E12, which are encoded by the E2A gene, regulate several stages of T cell development. In addition, mice deficient for E2A are highly susceptible to thymic lymphoma. Here we report that the development of lymphoma in E2A-deficient mice did not require pre- and r...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123255/ https://ncbi.nlm.nih.gov/pubmed/12172006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162373999 |
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