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E2A proteins enforce a proliferation checkpoint in developing thymocytes
E2A proteins regulate multiple stages of thymocyte development and suppress T-cell lymphoma. The activity of E2A proteins throughout thymocyte development is modulated by signals emanating from the pre-TCR and TCR. Here we demonstrate that E2A is required for the complete arrest in both differentiat...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1271657/ https://ncbi.nlm.nih.gov/pubmed/14685278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600017 |
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