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Mismatch-targeted transposition of Mu: A new strategy to map genetic polymorphism
Phage Mu DNA transposes to duplex target DNA sites with limited sequence specificity. Here we demonstrate that Mu transposition exhibits a strong target site preference for all single-nucleotide mismatches. This finding has implications for the mechanism of transposition and provides a powerful tool...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123254/ https://ncbi.nlm.nih.gov/pubmed/12177413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132403399 |
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