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Mismatch-targeted transposition of Mu: A new strategy to map genetic polymorphism

Phage Mu DNA transposes to duplex target DNA sites with limited sequence specificity. Here we demonstrate that Mu transposition exhibits a strong target site preference for all single-nucleotide mismatches. This finding has implications for the mechanism of transposition and provides a powerful tool...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yanagihara, Katsuhiko, Mizuuchi, Kiyoshi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2002
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC123254/
https://ncbi.nlm.nih.gov/pubmed/12177413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132403399
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