Mismatch-targeted transposition of Mu: A new strategy to map genetic polymorphism
Phage Mu DNA transposes to duplex target DNA sites with limited sequence specificity. Here we demonstrate that Mu transposition exhibits a strong target site preference for all single-nucleotide mismatches. This finding has implications for the mechanism of transposition and provides a powerful tool...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12177413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.132403399 |
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