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MHC heterozygosity confers a selective advantage against multiple-strain infections

Genetic heterozygosity is thought to enhance resistance of hosts to infectious diseases, but few tests of this idea exist. In particular, heterozygosity at the MHC, the highly polymorphic loci that control immunological recognition of pathogens, is suspected to confer a selective advantage by enhanc...

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Bibliografiske detaljer
Main Authors: Penn, Dustin J., Damjanovich, Kristy, Potts, Wayne K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC123244/
https://ncbi.nlm.nih.gov/pubmed/12177415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162006499
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