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Immunogenetic novelty confers a selective advantage in host–pathogen coevolution
The major histocompatibility complex (MHC) is crucial to the adaptive immune response of vertebrates and is among the most polymorphic gene families known. Its high diversity is usually attributed to selection imposed by fast-evolving pathogens. Pathogens are thought to evolve to escape recognition...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5816137/ https://ncbi.nlm.nih.gov/pubmed/29339521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708597115 |
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