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Immunogenetic novelty confers a selective advantage in host–pathogen coevolution
The major histocompatibility complex (MHC) is crucial to the adaptive immune response of vertebrates and is among the most polymorphic gene families known. Its high diversity is usually attributed to selection imposed by fast-evolving pathogens. Pathogens are thought to evolve to escape recognition...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5816137/ https://ncbi.nlm.nih.gov/pubmed/29339521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708597115 |
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