Combined Conjugate Vaccines: Enhanced Immunogenicity with the N19 Polyepitope as a Carrier Protein

The N19 polyepitope, consisting of a sequential string of universal human CD4(+)-T-cell epitopes, was tested as a carrier protein in a formulation of combined glycoconjugate vaccines containing the capsular polysaccharides (PSs) of Neisseria meningitidis serogroups A, C, W-135, and Y. Good antibody...

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Detalhes bibliográficos
Main Authors: Baraldo, Karin, Mori, Elena, Bartoloni, Antonella, Norelli, Francesco, Grandi, Guido, Rappuoli, Rino, Finco, Oretta, Del Giudice, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231108/
https://ncbi.nlm.nih.gov/pubmed/16113302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.5835-5841.2005
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