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Immunogenicity of Recombinant Protective Antigen and Efficacy against Aerosol Challenge with Anthrax

Immunization with a recombinant form of the protective antigen (rPA) from Bacillus anthracis has been carried out with rhesus macaques. Rhesus macaques immunized with 25 μg or more of B. subtilis-expressed rPA bound to alhydrogel had a significantly increased immunoglobulin G (IgG) response to rPA c...

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Detalhes bibliográficos
Main Authors: Williamson, E. D., Hodgson, I., Walker, N. J., Topping, A. W., Duchars, M. G., Mott, J. M., Estep, J., LeButt, C., Flick-Smith, H. C., Jones, H. E., Li, H., Quinn, C. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231098/
https://ncbi.nlm.nih.gov/pubmed/16113318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.5978-5987.2005
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