Efficacy and Immunogenicity of Single-Dose AdVAV Intranasal Anthrax Vaccine Compared to Anthrax Vaccine Absorbed in an Aerosolized Spore Rabbit Challenge Model

AdVAV is a replication-deficient adenovirus type 5-vectored vaccine expressing the 83-kDa protective antigen (PA83) from Bacillus anthracis that is being developed for the prevention of disease caused by inhalation of aerosolized B. anthracis spores. A noninferiority study comparing the efficacy of...

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Dettagli Bibliografici
Pubblicato in:Clin Vaccine Immunol
Autori principali: Krishnan, Vyjayanthi, Andersen, Bo H., Shoemaker, Christine, Sivko, Gloria S., Tordoff, Kevin P., Stark, Gregory V., Zhang, Jianfeng, Feng, Tsungwei, Duchars, Matthew, Roberts, M. Scot
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375354/
https://ncbi.nlm.nih.gov/pubmed/25673303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00690-14
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