Evaluation of Early Immune Response-Survival Relationship in Cynomolgus Macaques after Anthrax Vaccine Adsorbed Vaccination and Bacillus anthracis Spore Challenge

Anthrax vaccine adsorbed (AVA, BioThrax) is approved by the US Food and Drug Administration for post-exposure prophylaxis (PEP) of anthrax in adults. The PEP schedule is 3 subcutaneous (SC) doses (0, 14 and 28 days), in conjunction with a 60 day course of antimicrobials. The objectives of this study...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Sivko, GS, Stark, GV, Tordoff, KP, Taylor, KL, Glaze, E, VanRaden, M, Schiffer, JM, Hewitt, JA, Quinn, CP, Nuzum, EO
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097032/
https://ncbi.nlm.nih.gov/pubmed/27155494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.04.048
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