Enterotoxin-Based Mucosal Adjuvants Alter Antigen Trafficking and Induce Inflammatory Responses in the Nasal Tract

The safety of nasal vaccines containing enterotoxin-based mucosal adjuvants has not been studied in detail. Previous studies have indicated that native cholera toxin (nCT) can alter antigen trafficking when applied nasally. In this study, we determined the enterotoxin-based variables that alter anti...

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Hlavní autoři: van Ginkel, Frederik W., Jackson, Raymond J., Yoshino, Naoto, Hagiwara, Yukari, Metzger, Daniel J., Connell, Terry D., Vu, Hong L., Martin, Michael, Fujihashi, Kohtaro, McGhee, Jerry R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230900/
https://ncbi.nlm.nih.gov/pubmed/16177369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6892-6902.2005
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