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FLIP switches Fas-mediated glucose signaling in human pancreatic β cells from apoptosis to cell replication
Type 2 diabetes mellitus results from an inadequate adaptation of the functional pancreatic β cell mass in the face of insulin resistance. Changes in the concentration of glucose play an essential role in the regulation of β cell turnover. In human islets, elevated glucose concentrations impair β ce...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123051/ https://ncbi.nlm.nih.gov/pubmed/12060768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122686299 |
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