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Tau is essential to β-amyloid-induced neurotoxicity

Senile plaques and neurofibrillary tangles, the two hallmark lesions of Alzheimer's disease, are the results of the pathological deposition of proteins normally present throughout the brain. Senile plaques are extracellular deposits of fibrillar β-amyloid peptide (Aβ); neurofibrillary tangles r...

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Main Authors: Rapoport, Mark, Dawson, Hana N., Binder, Lester I., Vitek, Michael P., Ferreira, Adriana
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC122954/
https://ncbi.nlm.nih.gov/pubmed/11959919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092136199
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