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Tau is essential to β-amyloid-induced neurotoxicity

Senile plaques and neurofibrillary tangles, the two hallmark lesions of Alzheimer's disease, are the results of the pathological deposition of proteins normally present throughout the brain. Senile plaques are extracellular deposits of fibrillar β-amyloid peptide (Aβ); neurofibrillary tangles r...

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Detalhes bibliográficos
Main Authors: Rapoport, Mark, Dawson, Hana N., Binder, Lester I., Vitek, Michael P., Ferreira, Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122954/
https://ncbi.nlm.nih.gov/pubmed/11959919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092136199
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