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The Generation of a 17 kDa Neurotoxic Fragment: An Alternative Mechanism by which Tau Mediates β-Amyloid-Induced Neurodegeneration

Recently, we have shown that the microtubule-associated protein tau is essential for β-amyloid (Aβ)-induced neurotoxicity in hippocampal neurons. However, the mechanisms by which tau mediates Aβ-induced neurite degeneration remain poorly understood. In the present study, we analyzed whether tau clea...

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Detalhes bibliográficos
Main Authors: Park, So-Young, Ferreira, Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352316/
https://ncbi.nlm.nih.gov/pubmed/15930385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1125-05.2005
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