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Inclusion body myositis-like phenotype induced by transgenic overexpression of βAPP in skeletal muscle

Inclusion body myositis (IBM), the most common age-related muscle disease in the elderly population, is an incurable disorder leading to severe disability. Sporadic IBM has an unknown etiology, although affected muscle fibers are characterized by many of the pathobiochemical alterations traditionall...

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Tallennettuna:
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Sugarman, Michael C., Yamasaki, Tritia R., Oddo, Salvatore, Echegoyen, Julio C., Murphy, M. Paul, Golde, Todd E., Jannatipour, Mehrdad, Leissring, Malcolm A., LaFerla, Frank M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2002
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122949/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11972038/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.082545599
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