Inclusion body myositis-like phenotype induced by transgenic overexpression of βAPP in skeletal muscle

Inclusion body myositis (IBM), the most common age-related muscle disease in the elderly population, is an incurable disorder leading to severe disability. Sporadic IBM has an unknown etiology, although affected muscle fibers are characterized by many of the pathobiochemical alterations traditionall...

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Main Authors: Sugarman, Michael C., Yamasaki, Tritia R., Oddo, Salvatore, Echegoyen, Julio C., Murphy, M. Paul, Golde, Todd E., Jannatipour, Mehrdad, Leissring, Malcolm A., LaFerla, Frank M.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2002
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC122949/
https://ncbi.nlm.nih.gov/pubmed/11972038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082545599
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