Inclusion body myositis-like phenotype induced by transgenic overexpression of βAPP in skeletal muscle

Inclusion body myositis (IBM), the most common age-related muscle disease in the elderly population, is an incurable disorder leading to severe disability. Sporadic IBM has an unknown etiology, although affected muscle fibers are characterized by many of the pathobiochemical alterations traditionall...

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Detalhes bibliográficos
Main Authors: Sugarman, Michael C., Yamasaki, Tritia R., Oddo, Salvatore, Echegoyen, Julio C., Murphy, M. Paul, Golde, Todd E., Jannatipour, Mehrdad, Leissring, Malcolm A., LaFerla, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122949/
https://ncbi.nlm.nih.gov/pubmed/11972038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082545599
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