Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L

Dilated cardiomyopathy is a frequent cause of heart failure and is associated with high mortality. Progressive remodeling of the myocardium leads to increased dimensions of heart chambers. The role of intracellular proteolysis in the progressive remodeling that underlies dilated cardiomyopathy has n...

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Bibliographische Detailangaben
Hauptverfasser: Stypmann, Jörg, Gläser, Kerstin, Roth, Wera, Tobin, Desmond J., Petermann, Ivonne, Matthias, Rainer, Mönnig, Gerold, Haverkamp, Wilhelm, Breithardt, Günter, Schmahl, Wolfgang, Peters, Christoph, Reinheckel, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2002
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC122932/
https://ncbi.nlm.nih.gov/pubmed/11972068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092637699
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