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The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling

We have previously shown that the ubiquitously expressed lysosomal cysteine protease, cathepsin L (CTSL), is essential for skin and hair follicle homeostasis. Here we examine the effect of CTSL deficiency on hair follicle development and cycling in ctsl(−/−) mice by light and electron microscopy, Ki...

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Hlavní autoři: Tobin, Desmond J., Foitzik, Kerstin, Reinheckel, Thomas, Mecklenburg, Lars, Botchkarev, Vladimir A., Peters, Christoph, Paus, Ralf
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850854/
https://ncbi.nlm.nih.gov/pubmed/12000732
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