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Structural basis for Hif-1α/CBP recognition in the cellular hypoxic response
The cellular response to low tissue oxygen concentrations is mediated by the hypoxia-inducible transcription factor HIF-1. Under hypoxic conditions, HIF-1 activates transcription of critical adaptive genes by recruitment of the general coactivators CBP/p300 through interactions with its α-subunit (H...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122759/ https://ncbi.nlm.nih.gov/pubmed/11959977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082121399 |
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