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Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts

Myc is a transcriptional regulator of the basic helix–loop–helix leucine zipper protein family. It has strong oncogenic potential, mutated or virally transduced forms of Myc induce lymphoid tumors in animals, and deregulated expression of Myc is associated with numerous types of human cancers. For i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Berg, Thorsten, Cohen, Steven B., Desharnais, Joel, Sonderegger, Corinna, Maslyar, Daniel J., Goldberg, Joel, Boger, Dale L., Vogt, Peter K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC122609/
https://ncbi.nlm.nih.gov/pubmed/11891322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062036999
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