Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts

Myc is a transcriptional regulator of the basic helix–loop–helix leucine zipper protein family. It has strong oncogenic potential, mutated or virally transduced forms of Myc induce lymphoid tumors in animals, and deregulated expression of Myc is associated with numerous types of human cancers. For i...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Berg, Thorsten, Cohen, Steven B., Desharnais, Joel, Sonderegger, Corinna, Maslyar, Daniel J., Goldberg, Joel, Boger, Dale L., Vogt, Peter K.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122609/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11891322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.062036999
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