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Evidence of Linkage with HLA-DR in DRB1*15-Negative Families with Multiple Sclerosis

The importance of the HLA-DR locus to multiple sclerosis (MS) susceptibility was assessed in 542 sib pairs with MS and in their families. By genotyping 1,978 individuals for HLA-DRB1 alleles, we confirmed the well-established association of MS with HLA-DRB1*15 (HLA-DRB1*1501 and HLA-DRB5*0101), by t...

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Detalhes bibliográficos
Main Authors: Ligers, Arturs, Dyment, David A., Willer, Cristen J., Sadovnick, A. Dessa, Ebers, George, Risch, Neil, Hillert, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1226077/
https://ncbi.nlm.nih.gov/pubmed/11519010
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