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Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes

Juvenile diabetes (type 1) is an autoimmune disease in which CD4(+) T cells play a major role in pathogenesis characterized by insulitis and β cell destruction leading to clinical hyperglycemia. To date, no marker for autoimmune T cells has been described, although it was previously demonstrated tha...

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Detalhes bibliográficos
Main Authors: Wagner, David H., Vaitaitis, Gisela, Sanderson, Richard, Poulin, Michelle, Dobbs, Cathleen, Haskins, Kathryn
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122601/
https://ncbi.nlm.nih.gov/pubmed/11891296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052247099
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