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Up-regulation of nitric oxide synthase and modulation of the guanylate cyclase activity by corticotropin-releasing hormone but not urocortin II or urocortin III in cultured human pregnant myometrial cells

The biological actions of corticotropin-releasing hormone (CRH) in the human myometrium during pregnancy and labor are unknown. We hypothesized that CRH may modulate the nitric oxide system, and influence myometrial relaxation/contractility. Incubation of myometrial cells with CRH, but not urocortin...

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Detalhes bibliográficos
Main Authors: Aggelidou, Eleni, Hillhouse, Edward W., Grammatopoulos, Dimitris K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122513/
https://ncbi.nlm.nih.gov/pubmed/11854458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052296399
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