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EGCG inhibits cancer cell migration through inhibition of nitric oxide synthase and guanylate cyclase

Tumor cell migration is considered as a major event in the metastatic cascade. Here we examined the effect of (−)-epigallocatechin-3-gallate (EGCG) on migration capacity and molecular mechanism using 4T1 murine mammary cancer cells as a model. Using an in vitro migration assay, we found that treatme...

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Main Authors: Punathil, Thejass, Tollefsbol, Trygve O., Katiyar, Santosh K.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568882/
https://ncbi.nlm.nih.gov/pubmed/18692479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.07.157
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