Tissue transglutaminase-induced alterations in extracellular matrix inhibit tumor invasion

BACKGROUND: Alterations in the extracellular matrix (ECM) can affect host-tumor interactions and tumor growth and metastasis. Tissue transglutaminase (TG2, EC 2.3.2.13), a calcium-dependent enzyme that catalyzes covalent cross-linking of proteins, can render the ECM highly stable and resistant to pr...

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Bibliografiske detaljer
Main Authors: Mangala, Lingegowda S, Arun, Banu, Sahin, Aysegul A, Mehta, Kapil
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224867/
https://ncbi.nlm.nih.gov/pubmed/16153302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-4-33
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