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Tumor Microenvironment: Extracellular Matrix Alterations Influence Tumor Progression

The tumor microenvironment (TME) is composed of various cell types embedded in an altered extracellular matrix (ECM). ECM not only serves as a support for tumor cell but also regulates cell–cell or cell–matrix cross-talks. Alterations in ECM may be induced by hypoxia and acidosis, by oxygen free rad...

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Veröffentlicht in:Front Oncol
Hauptverfasser: Brassart-Pasco, Sylvie, Brézillon, Stéphane, Brassart, Bertrand, Ramont, Laurent, Oudart, Jean-Baptiste, Monboisse, Jean Claude
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174611/
https://ncbi.nlm.nih.gov/pubmed/32351878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00397
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