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Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans

5-Aminolevulinate synthase (ALAS) is the first and rate-limiting enzyme of heme biosynthesis in humans, animals, other non-plant eukaryotes, and α-proteobacteria. It catalyzes the synthesis of 5-aminolevulinic acid, the first common precursor of all tetrapyrroles, from glycine and succinyl-coenzyme...

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Detaylı Bibliyografya
Asıl Yazarlar: Astner, Isabel, Schulze, Jörg O, van den Heuvel, Joop, Jahn, Dieter, Schubert, Wolf-Dieter, Heinz, Dirk W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224682/
https://ncbi.nlm.nih.gov/pubmed/16121195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600792
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