Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice

We and others previously reported that cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the severity of peptide-induced experimental autoimmune encephalomyelitis (EAE) in mouse strains that are inherently susceptible to the disease. In this report, we show that CTLA-4 engagement also controls dis...

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Bibliographic Details
Main Authors: Hurwitz, Arthur A., Sullivan, Timothy J., Sobel, Raymond A., Allison, James P.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC122464/
https://ncbi.nlm.nih.gov/pubmed/11867713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042684699
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