α-Helical stabilization by side chain shielding of backbone hydrogen bonds
We study atomic models of the thermodynamics of the structural transition of peptides that form α-helices. The effect of sequence variation on α-helix formation for alanine-rich peptides, Ac-Ala(21)- methyl amide (A21) and Ac-A(5) (AAARA)(3)A-methyl amide (Fs peptide), is investigated by atomic simu...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122425/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.042496899 |
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