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α-Helical stabilization by side chain shielding of backbone hydrogen bonds
We study atomic models of the thermodynamics of the structural transition of peptides that form α-helices. The effect of sequence variation on α-helix formation for alanine-rich peptides, Ac-Ala(21)- methyl amide (A21) and Ac-A(5) (AAARA)(3)A-methyl amide (Fs peptide), is investigated by atomic simu...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122425/ https://ncbi.nlm.nih.gov/pubmed/11867710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042496899 |
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