Peptide fragments of the dihydropyridine receptor can modulate cardiac ryanodine receptor channel activity and sarcoplasmic reticulum Ca2+ release.

We show that peptide fragments of the dihydropyridine receptor II-III loop alter cardiac RyR (ryanodine receptor) channel activity in a cytoplasmic Ca2+-dependent manner. The peptides were AC (Thr-793-Ala-812 of the cardiac dihydropyridine receptor), AS (Thr-671-Leu-690 of the skeletal dihydropyridi...

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Hauptverfasser: Dulhunty, Angela F, Curtis, Suzanne M, Cengia, Louise, Sakowska, Magdalena, Casarotto, Marco G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224045/
https://ncbi.nlm.nih.gov/pubmed/14678014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031096
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