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The TRAP/Mediator coactivator complex interacts directly with estrogen receptors α and β through the TRAP220 subunit and directly enhances estrogen receptor function in vitro

Target gene activation by nuclear hormone receptors, including estrogen receptors (ERs), is thought to be mediated by a variety of interacting cofactors. Here we identify a number of nuclear extract-derived proteins that interact with immobilized ER ligand binding domains in a 17β-estradiol-dependen...

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Detalhes bibliográficos
Main Authors: Kang, Yun Kyoung, Guermah, Mohamed, Yuan, Chao-Xing, Roeder, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122401/
https://ncbi.nlm.nih.gov/pubmed/11867769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261715899
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