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Structural and Functional Organization of TRAP220, the TRAP/Mediator Subunit That Is Targeted by Nuclear Receptors

The TRAP/Mediator complex serves as a coactivator for many transcriptional activators, including nuclear receptors such as the thyroid hormone receptor (TR) that targets the TRAP220 subunit. The critical but selective function of TRAP220 is evidenced by the embryonic lethal phenotype of Trap220(−)(/...

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Autori principali: Malik, Sohail, Guermah, Mohamed, Yuan, Chao-Xing, Wu, Weizhen, Yamamura, Soichiro, Roeder, Robert G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC515042/
https://ncbi.nlm.nih.gov/pubmed/15340084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.8244-8254.2004
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