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BmTx3, a scorpion toxin with two putative functional faces separately active on A-type K+ and HERG currents.

A novel HERG channel blocker was isolated from the venom of the scorpion Buthus martensi Karsch, sequenced and characterized at the pharmacological level after chemical synthesis. According to the determined amino acid sequence, the cDNA and genomic genes were then cloned. The genomic gene consists...

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Detalhes bibliográficos
Main Authors: Huys, Isabelle, Xu, Chen-Qi, Wang, Cheng-Zhong, Vacher, Hélène, Martin-Eauclaire, Marie-France, Chi, Cheng-Wu, Tytgat, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223995/
https://ncbi.nlm.nih.gov/pubmed/14599291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031324
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