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Bax-induced cytochrome c release from mitochondria depends on alpha-helices-5 and -6.
The pro-apoptotic protein Bax plays a key role in the mitochondrial signalling pathway. Upon induction of apoptosis, Bax undergoes a conformational change and translocates to mitochondrial membranes, where it inserts and mediates the release of cytochrome c from the intermembrane space into the cyto...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223939/ https://ncbi.nlm.nih.gov/pubmed/14614769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031152 |
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