Phosphorylation of 20S proteasome alpha subunit C8 (alpha7) stabilizes the 26S proteasome and plays a role in the regulation of proteasome complexes by gamma-interferon.

In animal cells there are several regulatory complexes which interact with 20S proteasomes and give rise to functionally distinct proteasome complexes. gamma-Interferon upregulates three immuno beta catalytic subunits of the 20S proteasome and the PA28 regulator, and decreases the level of 26S prote...

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Main Authors: Bose, Suchira, Stratford, Fiona L L, Broadfoot, Kerry I, Mason, Grant G F, Rivett, A Jennifer
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223927/
https://ncbi.nlm.nih.gov/pubmed/14583091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031122
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