INTERFERON ALPHA TREATMENT OF PATIENTS WITH IMPAIRED INTERFERON GAMMA SIGNALING

Patients with deficiency in the interferon gamma receptor (IFN-γR) are unable to respond properly to IFN-γ and develop severe infections with nontuberculous mycobacteria (NTM). IFN-γ and IFN-α are known to signal through STAT1 and activate many downstream effector genes in common. Therefore, we adde...

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Detalhes bibliográficos
Main Authors: Bax, HI, Freeman, AF, Ding, L, Hsu, AP, Marciano, B, Kristosturyan, E, Jancel, T, Spalding, C, Pechacek, J, Olivier, KN, Barnhart, LA, Boris, L, Frein, C, Claypool, RJ, Anderson, V, Zerbe, CS, Holland, SM, Sampaio, EP
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136390/
https://ncbi.nlm.nih.gov/pubmed/23512243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-013-9882-5
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